Likely change indexes improve estimates of individual change on patient-reported outcomes.

ABSTRACT:

Purpose

Individual change on a patient-reported outcome (PRO) measure can be assessed by statistical significance and meaningfulness to patients. We explored the relationship between these two criteria by varying the confidence levels of the coefficient of repeatability (CR) on the Patient-Reported Outcomes Measurement Information System (R) Physical Function (PF) 10a (PF10a) measure.

Methods

In a sample of 1129 adult cancer patients, we estimated individual-change thresholds on the PF10a from baseline to 6 weeks later with the CR at 50%, 68%, and 95% confidence. We also assessed agreement with group- and individual-level thresholds from anchor-based methods [mean change and receiver operating characteristic (ROC) curve] using a PF-specific patient global impression of chang

SUBMITTER: Peipert JD 

PROVIDER: S-EPMC9994541 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature