Fracture prevalence and its association with bone density among children living with HIV in Zimbabwe.

ABSTRACT:

Objectives

HIV infection impairs bone density in children living with HIV (CLWH). We aimed to determine the prevalence of self-reported fracture (past or current), associated risk factors and disability, by HIV status in Zimbabwean children.

Design

Cross-sectional study.

Methods

We recruited CLWH aged 8-16 years taking antiretroviral therapy (ART) for ≥2 years from HIV clinics, and HIV-uninfected children from schools in Harare. Interviewer-administered questionnaires collected data on fracture site and management, sociodemographics, dietary calcium and vitamin D, physical activity and HIV history. Dual-energy X-ray absorptiometry (DXA) measured size-adjusted bone density.

Results

We recruited 303 CLWH [mean (SD) age 12.5 (2.5) years; 50% female] and 306 childr

SUBMITTER: Rukuni R 

PROVIDER: S-EPMC9994799 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature