Association Between rs2200733 Polymorphism of PITX2 Gene and the Risk of Atrial Fibrillation.

ABSTRACT:

Background

As observed in recent genetic studies, PITX2 is one of the most popular genes with atrial fibrillation; single nucleotide polymorphism (rs2200733) at chromosome 4q25 (near PITX2) is found to be strongly associated with atrial fibrillation, but it has a difference among Chinese Han population. The basic aim of conducting this study is to find the correlation between PITX2 gene polymorphism and the risk of atrial fibrillation and to identify the possibility for early diagnosis of silent atrial fibrillation and high-risk atrial fibrillation.

Methods

The study included 98 cases of atrial fibrillation patients and 88 non-atrial fibrillation patients in Affiliated Hospital of Yangzhou University were enrolled in a case-control study. The single nucleotide polymorphism o

SUBMITTER: Shen Han Y 

PROVIDER: S-EPMC9995556 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature