Pregnancy in women living with perinatally acquired HIV: Perinatal outcomes and drug resistance profile.

ABSTRACT:

Objectives

To analyze the perinatal outcomes of Perinatally acquired HIV Infection (PHIV) in pregnant women.

Method

This retrospective cohort study included singleton pregnancies in Women Living with HIV (WLH) between 2006 and 2019. Patient charts were revised, and maternal characteristics, type of HIV infection (perinatal vs. behavioral), Antiretroviral Therapy (ART) exposure, and obstetric and neonatal outcomes were assessed. The HIV-related aspects considered were: Viral Load (VL), CD4+ cell count, opportunistic infections, and genotype testing. Laboratory analyses were performed at baseline (first appointment) and 34 weeks of gestation.

Results

There were 186 WLH pregnancies, and 54 (29%) patients had PHIV. Patients with PHIV were younger (p < 0.001), had less fre

SUBMITTER: Osmundo GS 

PROVIDER: S-EPMC9995930 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature