Renal outcomes of rivaroxaban compared with warfarin in Asian patients with nonvalvular atrial fibrillation: A nationwide population-based cohort study.

ABSTRACT:

Background

Further studies are needed to expand the evidence for the association of rivaroxaban with a lower risk of adverse renal outcomes in patients with atrial fibrillation (AF) as compared with warfarin, especially in Asians.

Objectives

To determine whether there are differences in adverse renal outcomes between rivaroxaban and warfarin-treated AF patients.

Methods

Using the Korean nationwide claims database partly linked to laboratory results, patients with AF who initiated warfarin or rivaroxaban from 1 January 2014 to 31 December 2017 were identified. Inverse probability of treatment weighting (IPTW) was used to balance the baseline characteristics of the two groups. The primary outcome (kidney failure) was defined as the need for maintenance dialysis or havin

SUBMITTER: Lee SR 

PROVIDER: S-EPMC9996329 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature