Transfusion medicine approaches for spontaneous intracerebral hemorrhage patients.

ABSTRACT:

Purpose of review

Spontaneous intracerebral hemorrhage (ICH) is the deadliest stroke subtype. Acute treatments necessitate rapid hemorrhage control to minimize secondary brain injury. Here, we discuss the overlap of transfusion medicine and acute ICH care relating to diagnostic testing and therapies relevant for coagulopathy reversal and secondary brain injury prevention.

Recent findings

Hematoma expansion (HE) is the largest contributor to poor outcomes after ICH. Conventional coagulation assays to diagnose coagulopathy after ICH does not predict HE. Given the testing limitations, empiric pragmatic hemorrhage control therapies have been trialed but have not improved ICH outcomes, with some therapies even causing harm. It is still unknown whether faster administration of the

SUBMITTER: Stone EF 

PROVIDER: S-EPMC9996464 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature