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Integrated Glass Microfluidics with Electrochemical Nanogap Electrodes.

ABSTRACT: We present a framework for the fabrication of chip-based electrochemical nanogap sensors integrated with microfluidics. Instead of polydimethylsiloxane (PDMS), SU-8 aided adhesive bonding of silicon and glass wafers is used to implement parallel flow control. The fabrication process permits wafer-scale production with high throughput and reproducibility. Additionally, the monolithic structures allow simple electrical and fluidic connections, alleviating the need for specialized equipment. We demonstrate the utility of these flow-incorporated nanogap sensors by performing redox cycling measurements under laminar flow conditions.

SUBMITTER: Sarkar S

PROVIDER: S-EPMC9996602 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature

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Integrated Glass Microfluidics with Electrochemical Nanogap Electrodes.

Sarkar Sahana S Nieuwenhuis Ab F AF Lemay Serge G SG

Analytical chemistry 20230222 9

We present a framework for the fabrication of chip-based electrochemical nanogap sensors integrated with microfluidics. Instead of polydimethylsiloxane (PDMS), SU-8 aided adhesive bonding of silicon and glass wafers is used to implement parallel flow control. The fabrication process permits wafer-scale production with high throughput and reproducibility. Additionally, the monolithic structures allow simple electrical and fluidic connections, alleviating the need for specialized equipment. We dem ...[more]

PMID: 36812004

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