Fabrication of a Lactate-Specific Molecularly Imprinted Polymer toward Disease Detection.

ABSTRACT: The development of sensitive and selective robust sensor materials for targeted biomarker detection aims to contribute to self-health monitoring and management. Molecularly imprinted polymeric (MIP) materials can perform as biomimetic recognition elements via tailored routes of synthesis for specific target analyte extraction and/or detection. In this work, a sensitive- and selective-lactate MIP has been developed utilizing methacrylic acid and ethylene glycol dimethacrylate as the functional monomer and cross-linker, respectively. The sensitivity of the as-synthesized imprinted species was evaluated by determining the target analyte retention, imprinting factor, and selectivity adsorption of up to 63.5%, 6.86, and 0.82, respectively. MIP selectivity elucidated the imprinting mechanism bet

SUBMITTER: Mustafa YL 

PROVIDER: S-EPMC9996612 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature