Revisiting Disinfection Byproducts with Supercritical Fluid Chromatography-High Resolution-Mass Spectrometry: Identification of Novel Halogenated Sulfonic Acids in Disinfected Drinking Water.

ABSTRACT: High resolution mass spectrometry (HRMS) coupled to either gas chromatography or reversed-phase liquid chromatography is the generic method to identify unknown disinfection byproducts (DBPs) but can easily overlook their highly polar fractions. In this study, we applied an alternative chromatographic separation method, supercritical fluid chromatography-HRMS, to characterize DBPs in disinfected water. In total, 15 DBPs were tentatively identified for the first time as haloacetonitrilesulfonic acids, haloacetamidesulfonic acids, and haloacetaldehydesulfonic acids. Cysteine, glutathione, and p-phenolsulfonic acid were found as precursors during lab-scale chlorination, with cysteine providing the highest yield. A mixture of the labeled analogues of these DBPs was prepared by chlorinati

SUBMITTER: Nihemaiti M 

PROVIDER: S-EPMC9996826 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature