Antimicrobial peptides act on the rumen microbiome and metabolome affecting the performance of castrated bulls.

ABSTRACT:

Background

Many countries have already banned the use of antibiotics in animal husbandry, making it extremely difficult to maintain animal health in livestock breeding. In the livestock industry, there is an urgent need to develop alternatives to antibiotics which will not lead to drug resistance on prolonged use. In this study, eighteen castrated bulls were randomly divided into two groups. The control group (CK) was fed the basal diet, while the antimicrobial peptide group (AP) was fed the basal diet supplemented with 8 g of antimicrobial peptides in the basal diet for the experimental period of 270 d. They were then slaughtered to measure production performance, and the ruminal contents were isolated for metagenomic and metabolome sequencing analysis.

Result

The results s

SUBMITTER: Shi J 

PROVIDER: S-EPMC9996874 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature