Food elimination diet is a viable alternative therapy for eosinophilic esophagitis responsive to proton pump inhibitors.

ABSTRACT:

Background

First-line treatment of eosinophilic esophagitis (EoE) includes monotherapy with proton-pump inhibitors (PPIs), food elimination diet (FED), or topical corticosteroids. Current guidelines suggest patients with EoE should continue any responsive first-line monotherapies. However, the efficacy of FED monotherapy in patients with EoE responsive to PPI monotherapy has not been well studied. Our study aimed to investigate how attempting FED monotherapy after experiencing remission of EoE after PPI monotherapy influenced long-term EoE management.

Methods

We retrospectively identified patients with EoE responsive to PPI monotherapy who trialed FED monotherapy. We then employed a mixed method approach to a prospective cohort. Selected patients were observed long term for

SUBMITTER: Sia T 

PROVIDER: S-EPMC9997030 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature