Molecular docking analysis of mTOR protein kinase with chromatographically characterized compounds from Clerodendrum inerme L. leaves extract.
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ABSTRACT:
SUBMITTER: Arumugam D
PROVIDER: S-EPMC9997495 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
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Molecular docking analysis of mTOR protein kinase with chromatographically characterized compounds from <i>Clerodendrum inerme L.</i> leaves extract.
Arumugam Dhanalakshmi D Ganesan Sasireka S Ayyakkalai Marikkannu Karthikeyan Kalimuthu KK
Bioinformation 20220430 4
The mTOR protein is known to be linked with cancer. Therefore, it is of interest to document the molecular docking analysis of mTOR protein kinase with chromatographically characterized compounds from Clerodendrum inerme L. leaves extract. The GC-MS analysis suggested that, totally 25 bioactive compounds were present in the extract of Clerodendrum inerme. Molecular docking analysis show that the bioactive compounds such as Triethoxysilanol, Piperazine dihydrochloridehydrate, 2,4(1H,3H)-Pyrimidin ...[more]
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