Treatment reality of patients with BRAF-mutant advanced/metastatic melanoma in Switzerland in the era of choice.

ABSTRACT: Cutaneous melanoma represents a major cause of cancer death in Europe. Without adequate therapy, the 5-year survival rate is 15-20% in distant metastatic disease. Evaluating the status quo of treatment standards in advanced melanoma and rationale for therapy decisions in Switzerland between January 2016 and September 2018. In this retrospective, anonymized registry, data of male and female patients with unresectable advanced/metastatic BRAF-positive cutaneous melanoma treated in first-, second- and third-line with registered substances were analyzed using descriptive statistics. Forty-one patients (56.1% male) were included providing a total of 70 treatment lines (first-line: n = 41; second-line: n = 18; and third-line: n = 11). Within the patients presenting with stage III or IV melanoma,

SUBMITTER: Mangana J 

PROVIDER: S-EPMC9997623 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature