A simultaneous EEG-fMRI study of thalamic load-dependent working memory delay period activity.

ABSTRACT:

Introduction

Working memory (WM) is an essential component of executive functions which depend on maintaining task-related information online for brief periods in both the presence and absence of interfering stimuli. Active maintenance occurs during the WM delay period, the time between stimulus encoding and subsequent retrieval. Previous studies have extensively documented prefrontal and posterior parietal cortex activity during the WM delay period, but the role of subcortical structures including the thalamus remains to be fully elucidated, especially in humans.

Methods

Using a simultaneous electroencephalogram (EEG)-functional magnetic resonance imaging (fMRI) approach, we investigated the role of the thalamus during the WM delay period in a modified Sternberg paradigm fo

SUBMITTER: Gomes BA 

PROVIDER: S-EPMC9997713 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature