A systematic review of economic evaluations of whole-genome sequencing for the surveillance of bacterial pathogens.

ABSTRACT: Whole-genome sequencing (WGS) has unparalleled ability to distinguish between bacteria, with many public health applications. The generation and analysis of WGS data require significant financial investment. We describe a systematic review summarizing economic analyses of genomic surveillance of bacterial pathogens, reviewing the evidence for economic viability. The protocol was registered on PROSPERO (CRD42021289030). Six databases were searched on 8 November 2021 using terms related to 'WGS', 'population surveillance' and 'economic analysis'. Quality was assessed with the Drummond-Jefferson checklist. Following data extraction, a narrative synthesis approach was taken. Six hundred and eighty-one articles were identified, of which 49 proceeded to full-text screening, with 9 selected for i

SUBMITTER: Price V 

PROVIDER: S-EPMC9997737 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature