Molecular targets and mechanisms involved in the action of Banxia Shumi decoction in insomnia treatment

ABSTRACT: Insomnia is a common sleep-wake rhythm disorder, which is closely associated with the occurrence of many serious diseases. Recent researches suggest that circadian rhythms play an important role in regulating sleep duration and sleep quality. Banxia Shumi decoction (BSXM) is a well-known Chinese formula used to treat insomnia in China. However, the overall molecular mechanism behind this therapeutic effect has not yet been fully elucidated. This study aimed to identify the molecular targets and mechanisms involved in the action of BSXM during the treatment of insomnia. Using network pharmacology and molecular docking methods, we investigated the molecular targets and underlying mechanisms of action of BSXM in insomnia therapy. We identified 8 active compounds from Traditional Chinese Medic

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC9997805 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature