Association of serum folate levels during pregnancy and prenatal depression.

ABSTRACT:

Objective

To evaluate the association between serum folate levels during pregnancy and prenatal depression and the extent to which obesity may modify this relationship.

Methods

This secondary data analysis leveraged data from a previous study of pregnant Kaiser Permanente Northern California participants who completed a survey and provided a serum sample between 2011 and 2013. Serum folate was assessed using the Center for Disease Control's Total Folate Serum/Whole Blood Microbiological Assay Method. A score of 15 or greater on the Center for Epidemiologic Studies Depression Scale was defined as prenatal depression. We used Poisson regression to estimate risk of prenatal depression given prenatal serum folate status (low/medium tertiles vs. high tertile) in the full sample a

SUBMITTER: Avalos LA 

PROVIDER: S-EPMC9997998 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature