Epidemiology of cardiac amyloidosis in Germany: a retrospective analysis from 2009 to 2018.

ABSTRACT:

Background

Improved imaging modalities contributed to increasing awareness of cardiac amyloidosis. Contemporary data on frequency trends in Germany are lacking.

Methods

In a retrospective study using health claims data of a German statutory health insurance, patients with diagnostic codes of amyloidosis and concomitant heart failure between 2009 and 2018 were identified.

Results

Prevalence increased from 15.5 to 47.6 per 100,000 person-years, and incidence increased from 4.8 to 11.6 per 100,000 person-years, with a continuous steepening in the slope of incidence trend. In patients with amyloidosis and heart failure age and proportion of men significantly increased, whereas the frequency of myeloma and nephrotic syndrome significantly decreased over time. Median (IQR)

SUBMITTER: Ney S 

PROVIDER: S-EPMC9998316 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature