Casein Kinase 2 Mediates HIV- and Opioid-Induced Pathologic Phosphorylation of TAR DNA Binding Protein 43 in the Basal Ganglia.

ABSTRACT:

Summary statement

HIV/HIV-1 Tat and morphine independently increase pathologic phosphorylation of TAR DNA binding protein 43 in the striatum. HIV- and opioid-induced pathologic phosphorylation of TAR DNA binding protein 43 may involve enhanced CK2 activity and protein levels.

SUBMITTER: Ohene-Nyako M 

PROVIDER: S-EPMC9998424 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature