Prognostic nomogram for estimating survival in patients with resected muscle-invasive bladder cancer receiving chemotherapy

ABSTRACT:

Background

Chemotherapy has been proven to bring survival benefit in patients with resected muscle-invasive bladder cancer (MIBC), which is increasingly recommended. Our objective was to establish an effective model for estimating the overall survival (OS) and cancer-specific survival (CSS) in these patients.

Methods

2,030 patients diagnosed with resected MIBC receiving chemotherapy were acquired from the Surveillance, Epidemiology, and End Result (SEER) database, which were randomized 7:3 into a primary set (1,421 patients) and an internal validation set (609 patients). Significant predictors for OS and CSS were identified by Cox regression models, which were then utilized to develop prognostic nomogram. The performance of the model was assessed by utilizing calibration,

SUBMITTER: Hu B 

PROVIDER: S-EPMC9998492 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature