Native T1 mapping for the diagnosis of cardiac amyloidosis in patients with left ventricular hypertrophy.

ABSTRACT:

Background

Cardiac magnetic resonance (CMR) with parametric mapping can improve the characterization of myocardial tissue. We studied the diagnostic value of native T1 mapping to detect cardiac amyloidosis in patients with left ventricular (LV) hypertrophy.

Methods

One hundred twenty-five patients with increased LV wall thickness (≥ 12 mm end-diastole) who received clinical CMR in a 3 T scanner between 2017 and 2020 were included. 31 subjects without structural heart disease served as controls. Native T1 was measured as global mean value from 3 LV short axis slices. The study was registered at German clinical trial registry (DRKS00022048).

Results

Mean age of the patients was 66 ± 14 years, 83% were males. CA was present in 24 patients, 21 patients had hypertrophic ca

SUBMITTER: Lavall D 

PROVIDER: S-EPMC9998594 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature