Impact of possible tardive dyskinesia on physical wellness and social functioning: results from the real-world RE-KINECT study.

ABSTRACT:

Background

Tardive dyskinesia (TD) is a persistent and potentially disabling movement disorder associated with antipsychotic use. Data from RE-KINECT, a real-world study of antipsychotic-treated outpatients, were analyzed to assess the effects of possible TD on patient health and social functioning.

Methods

Analyses were conducted in Cohort 1 (patients with no abnormal involuntary movements) and Cohort 2 (patients with possible TD per clinician judgment). Assessments included: EuroQoL's EQ-5D-5L utility (health); Sheehan Disability Scale (SDS) total score (social functioning); patient- and clinician-rated severity of possible TD ("none", "some", "a lot"); and patient-rated impact of possible TD ("none", "some", "a lot"). Regression models were used to analyze the following:

SUBMITTER: Tanner CM 

PROVIDER: S-EPMC9998754 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature