Eye Dynamics and Engineering Network Consortium: Baseline Characteristics of a Randomized Trial in Healthy Adults.

ABSTRACT:

Purpose

To improve understanding of intraocular pressure (IOP) and its variance, this project identifies systemic and ocular characteristics of healthy eyes of adult volunteers including IOP variation, ocular biometrics, and aqueous humor dynamics (AHDs). These data serve as baseline controls for further studies from the Eye Dynamics and Engineering Network (EDEN) Consortium.

Design

Multicenter open-label clinical trial in healthy adults randomized to 1 week treatment with 2 approved glaucoma drugs in a crossover design.

Participants

Among 135 healthy participants, 122 participants (aged 55.2 ± 8.8 years; 92 females, 30 males) completed the protocol.

Methods

Participants from the University of Michigan, Mayo Clinic, and University of Nebraska Medical Center und

SUBMITTER: Reed DM 

PROVIDER: S-EPMC9998773 | biostudies-literature | 2023 Mar-Apr

REPOSITORIES: biostudies-literature