Critically ill severe hypothyroidism: a retrospective multicenter cohort study.

ABSTRACT:

Background

Severe hypothyroidism (SH) is a rare but life-threatening endocrine emergency. Only a few data are available on its management and outcomes of the most severe forms requiring ICU admission. We aimed to describe the clinical manifestations, management, and in-ICU and 6-month survival rates of these patients.

Methods

We conducted a retrospective, multicenter study over 18 years in 32 French ICUs. The local medical records of patients from each participating ICU were screened using the International Classification of Disease 10th revision. Inclusion criteria were the presence of biological hypothyroidism associated with at least one cardinal sign among alteration of consciousness, hypothermia and circulatory failure, and at least one SH-related organ failure.

Resu

SUBMITTER: Bourcier S 

PROVIDER: S-EPMC9998819 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature