Metabolomics facilitates the discovery of metabolic profiles and pathways for myopia: A systematic review.

ABSTRACT:

Background

Myopia is one of the major eye disorders and the global burden is increasing rapidly. Our purpose is to systematically summarize potential metabolic biomarkers and pathways in myopia to facilitate the understanding of disease mechanisms as well as the discovery of novel therapeutic measures.

Methods

Myopia-related metabolomics studies were searched in electronic databases of PubMed and Web of Science until June 2021. Information regarding clinical and demographic characteristics of included studies and metabolomics findings were extracted. Myopia-related metabolic pathways were analysed for differential metabolic profiles, and the quality of included studies was assessed based on the QUADOMICS tool. Pathway analyses of differential metabolites were performed using

SUBMITTER: Hou XW 

PROVIDER: S-EPMC9998863 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature