Ontology highlight
ABSTRACT:
SUBMITTER: Kandwal S
PROVIDER: S-EPMC9999249 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature
Kandwal Shubhangi S Fayne Darren D
Virology 20230310
The majority of SARS-CoV-2 therapeutic development work has focussed on targeting the spike protein, viral polymerase and proteases. As the pandemic progressed, many studies reported that these proteins are prone to high levels of mutation and can become drug resistant. Thus, it is necessary to not only target other viral proteins such as the non-structural proteins (NSPs) but to also target the most conserved residues of these proteins. In order to understand the level of conservation among the ...[more]