Functional connectivity changes during working memory in autism spectrum disorder: A two-year longitudinal MEG study.

ABSTRACT: Working memory impairments have been reported in adults with autism spectrum disorder (ASD) and associated with functional outcomes and social difficulties. However, little is known about the developmental trajectory of working memory in youth with ASD. The current magnetoencephalography (MEG) study is the first to examine the longitudinal development over two years of working memory networks in youth with ASD. We analysed MEG data from 32 children and adolescents with and without ASD (64 datasets; 7-14 years), all tested twice at a two-year interval, during a visual n-back task, with two loads (1- and 2-back). We performed a whole-brain functional connectivity analysis to examine the networks during the successful recognition of visual stimuli. We demonstrate that youth with ASD show decr

SUBMITTER: Sato J 

PROVIDER: S-EPMC9999263 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature