Strategies for refinement of occupational inhalation exposure evaluation in the EPA TSCA risk evaluation process.

ABSTRACT: The focus on occupational exposures in the first published risk evaluations of existing chemicals by the Environmental Protection Agency (EPA) under the amended Toxic Substances Control Act (TSCA) puts a welcome spotlight on protecting the health of workers in the United States. Because new, fit-for-purpose occupational exposure assessment methodologies were developed by EPA, the objective of this analysis was to evaluate these methodologies in light of other existing occupational risk assessment frameworks. We focused our analysis on three chlorinated chemicals (methylene chloride, carbon tetrachloride, perchloroethylene). The EPA's methods were evaluated relative to peer-reviewed and professional organizations' guidelines for conducting site- and facility-based exposure assessment. Analy

SUBMITTER: Lynch HN 

PROVIDER: S-EPMC9999275 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature