Impact of oral statin therapy on clinical outcomes in patients with cT1 breast cancer.

ABSTRACT:

Purpose

A previous meta-analysis examining the relationship between statin use and breast cancer reported that the inhibitory effect of statins on breast cancer may be more pronounced in early-stage cases. In this study, we aimed to investigate the effects of hyperlipidemia treatment at the time of breast cancer diagnosis and to examine its correlation with metastasis to axillary lymph nodes among patients with so-called cT1 breast cancer whose primary lesion was 2 cm or less and was pathologically evaluated by sentinel lymph node biopsy or axillary lymph node dissection. We also investigated the effects of hyperlipidemic drugs on the prognosis of patients with early-stage breast cancer.

Methods

After excluding cases that did not meet the criteria, we analyzed data from 719

SUBMITTER: Takada K 

PROVIDER: S-EPMC9999569 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature