Metabolomic profiles in night shift workers: A cross-sectional study on hospital female nurses.

ABSTRACT:

Background and aim

Shift work, especially including night shifts, has been found associated with several diseases, including obesity, diabetes, cancers, and cardiovascular, mental, gastrointestinal and sleep disorders. Metabolomics (an omics-based methodology) may shed light on early biological alterations underlying these associations. We thus aimed to evaluate the effect of night shift work (NSW) on serum metabolites in a sample of hospital female nurses.

Methods

We recruited 46 nurses currently working in NSW in Milan (Italy), matched to 51 colleagues not employed in night shifts. Participants filled in a questionnaire on demographics, lifestyle habits, personal and family health history and work, and donated a blood sample. The metabolome was evaluated through a validate

SUBMITTER: Borroni E 

PROVIDER: S-EPMC9999616 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature