Noninvasive assessment of myocardial work during left ventricular isovolumic relaxation in patients with diastolic dysfunction.

ABSTRACT:

Background

This study aims to investigate the value of myocardial work (MW) parameters during the isovolumic relaxation (IVR) period in patients with left ventricular diastolic dysfunction (LVDD).

Methods

This study prospectively recruited 448 patients with risks for LVDD and 95 healthy subjects. An additional 42 patients with invasive measurements of left ventricular (LV) diastolic function were prospectively included. The MW parameters during IVR were noninvasively measured using EchoPAC.

Results

The total myocardial work during IVR (MW_IVR), myocardial constructive work during IVR (MCW_IVR), myocardial wasted work during IVR (MWW_IVR), and myocardial work efficiency during IVR (MWE_IVR) of these patients were 122.5 ± 60.1 mmH

SUBMITTER: Guo Y 

PROVIDER: S-EPMC9999647 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature