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Structure of the Z-disk isolated from the indirect flight muscle of the honey bee


ABSTRACT:

SUBMITTER: John Trinick 

PROVIDER: EMPIAR-10095 | biostudies-other |

REPOSITORIES: biostudies-other

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Structure of isolated Z-disks from honeybee flight muscle.

Rusu Mara M   Hu Zhongjun Z   Taylor Kenneth A KA   Trinick John J  

Journal of muscle research and cell motility 20170401 2


The Z-disk is a complex structure comprising some 40 proteins that are involved in the transmission of force developed during muscle contraction and in important signalling pathways that govern muscle homeostasis. In the Z-disk the ends of antiparallel thin filaments from adjacent sarcomeres are crosslinked by α-actinin. The structure of the Z-disk lattice varies greatly throughout the animal kingdom. In vertebrates the thin filaments form a tetragonal lattice, whereas invertebrate flight muscle  ...[more]

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