Ontology highlight
ABSTRACT:
SUBMITTER: Sjors Scheres
PROVIDER: EMPIAR-10424 | biostudies-other |
REPOSITORIES: biostudies-other

Nature 20201021 7832
The three-dimensional positions of atoms in protein molecules define their structure and their roles in biological processes. The more precisely atomic coordinates are determined, the more chemical information can be derived and the more mechanistic insights into protein function may be inferred. Electron cryo-microscopy (cryo-EM) single-particle analysis has yielded protein structures with increasing levels of detail in recent years<sup>1,2</sup>. However, it has proved difficult to obtain cryo ...[more]