Dataset Information
The CryoEM Structure of Drosophila Flight Muscle Thick Filaments at 7Å Resolution
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ABSTRACT:
SUBMITTER: Kenneth Allen Taylor
PROVIDER: EMPIAR-10436 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
CryoEM structure of <i>Drosophila</i> flight muscle thick filaments at 7 Å resolution.
Life science alliance 20200727 8
Striated muscle thick filaments are composed of myosin II and several non-myosin proteins. Myosin II's long α-helical coiled-coil tail forms the dense protein backbone of filaments, whereas its N-terminal globular head containing the catalytic and actin-binding activities extends outward from the backbone. Here, we report the structure of thick filaments of the flight muscle of the fruit fly <i>Drosophila melanogaster</i> at 7 Å resolution. Its myosin tails are arranged in curved molecular cryst ...[more]