Dataset Information
The Myosin II Coiled Coil Domain Atomic Structure in its Native Environment
Ontology highlight
ABSTRACT:
SUBMITTER: Kenneth Taylor
PROVIDER: EMPIAR-10675 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
The myosin II coiled-coil domain atomic structure in its native environment.
Proceedings of the National Academy of Sciences of the United States of America 20210401 14
The atomic structure of the complete myosin tail within thick filaments isolated from <i>Lethocerus indicus</i> flight muscle is described and compared to crystal structures of recombinant, human cardiac myosin tail segments. Overall, the agreement is good with three exceptions: the proximal S2, in which the filament has heads attached but the crystal structure doesn't, and skip regions 2 and 4. At the head-tail junction, the tail α-helices are asymmetrically structured encompassing well-defined ...[more]