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Bacteriophage PhiKZ non-virion RNA Polymerase


ABSTRACT:

SUBMITTER: Christopher Herbert Stanley Aylett 

PROVIDER: EMPIAR-10709 | biostudies-other |

REPOSITORIES: biostudies-other

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Bacteriophage ΦKZ (PhiKZ) is the archetype of a family of massive bacterial viruses. It is considered to have therapeutic potential as its host, Pseudomonas aeruginosa, is an opportunistic, intrinsically antibiotic resistant, pathogen that kills tens of thousands worldwide each year. ΦKZ is an incredibly interesting virus, expressing many systems that the host already possesses. On infection, it forms a 'nucleus', erecting a barrier around its genome to exclude host endonucleases and CRISPR-Cas  ...[more]

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