Dataset Information
Cryo-EM SPA dataset of Megadalton-range protein communities from a Chaetomium thermophilum native cell extract
Ontology highlight
ABSTRACT:
SUBMITTER: Panagiotis L. Kastritis
PROVIDER: EMPIAR-10892 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Cryo-EM and artificial intelligence visualize endogenous protein community members.
Structure (London, England : 1993) 20220131 4
Cellular function is underlined by megadalton assemblies organizing in proximity, forming communities. Metabolons are protein communities involving metabolic pathways such as protein, fatty acid, and thioesters of coenzyme-A synthesis. Metabolons are highly heterogeneous due to their function, making their analysis particularly challenging. Here, we simultaneously characterize metabolon-embedded architectures of a 60S pre-ribosome, fatty acid synthase, and pyruvate/oxoglutarate dehydrogenase com ...[more]