Dataset Information
Cryo-EM structure of Bacillus subtilis RNA Polymerase elongation complex
Ontology highlight
ABSTRACT:
SUBMITTER: Gokhan Tolun
PROVIDER: EMPIAR-11051 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Molecular basis for RNA polymerase-dependent transcription complex recycling by the helicase-like motor protein HelD.
Nature communications 20201218 1
In bacteria, transcription complexes stalled on DNA represent a major source of roadblocks for the DNA replication machinery that must be removed in order to prevent damaging collisions. Gram-positive bacteria contain a transcription factor HelD that is able to remove and recycle stalled complexes, but it was not known how it performed this function. Here, using single particle cryo-electron microscopy, we have determined the structures of Bacillus subtilis RNA polymerase (RNAP) elongation and H ...[more]