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Dataset Information

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MCRV virus


ABSTRACT:

SUBMITTER: Wen Jiang 

PROVIDER: EMPIAR-11616 | biostudies-other |

REPOSITORIES: biostudies-other

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Publications

The structure of a 12-segmented dsRNA reovirus: New insights into capsid stabilization and organization.

Zhang Qinfen Q   Gao Yuanzhu Y   Baker Matthew L ML   Liu Shanshan S   Jia Xudong X   Xu Haidong H   He Jianguo J   Kaelber Jason T JT   Weng Shaoping S   Jiang Wen W  

PLoS pathogens 20230421 4


Infecting a wide range of hosts, members of Reovirales (formerly Reoviridae) consist of a genome with different numbers of segmented double stranded RNAs (dsRNA) encapsulated by a proteinaceous shell and carry out genome replication and transcription inside the virion. Several cryo-electron microscopy (cryo-EM) structures of reoviruses with 9, 10 or 11 segmented dsRNA genomes have revealed insights into genome arrangement and transcription. However, the structure and genome arrangement of 12-seg  ...[more]

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