Dataset Information
Single particle cryo-EM dataset of mitochondrial respiratory complex I from Macaca mulatta
Ontology highlight
ABSTRACT:
SUBMITTER: Hannah Ruth Bridges
PROVIDER: EMPIAR-11672 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Mammalian Respiratory Complex I Through the Lens of Cryo-EM.
Annual review of biophysics 20190220
Single-particle electron cryomicroscopy (cryo-EM) has led to a revolution in structural work on mammalian respiratory complex I. Complex I (mitochondrial NADH:ubiquinone oxidoreductase), a membrane-bound redox-driven proton pump, is one of the largest and most complicated enzymes in the mammalian cell. Rapid progress, following the first 5-Å resolution data on bovine complex I in 2014, has led to a model for mouse complex I at 3.3-Å resolution that contains 96% of the 8,518 residues and to the i ...[more]