Ontology highlight
ABSTRACT:
SUBMITTER: Gabriele Cerutti
PROVIDER: EMPIAR-11871 | biostudies-other |
REPOSITORIES: biostudies-other
Cell reports 20220207 9
The recently reported B.1.1.529 Omicron variant of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) includes 34 mutations in the spike protein relative to the Wuhan strain, including 15 mutations in the receptor-binding domain (RBD). Functional studies have shown Omicron to substantially escape the activity of many SARS-CoV-2-neutralizing antibodies. Here, we report a 3.1 Å-resolution cryoelectron microscopy (cryo-EM) structure of the Omicron spike protein ectodomain. The structure d ...[more]