Dataset Information
Cryo-ET dataset of dormant microsporidian spores from Encephalitozoon hellem
Ontology highlight
ABSTRACT:
SUBMITTER: Mahrukh Usmani
PROVIDER: EMPIAR-12175 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Cryo-ET reveals the in situ architecture of the polar tube invasion apparatus from microsporidian parasites.
Proceedings of the National Academy of Sciences of the United States of America 20250311 11
Microsporidia are divergent fungal pathogens that employ a unique harpoon-like apparatus called the polar tube (PT) to invade host cells. The long PT is fired out of the microsporidian spore over the course of just a few hundred milliseconds. Once fired, the PT is thought to pierce the plasma membrane of a target cell and act as a conduit for the transfer of the parasite into the host cell, which initiates infection. The PT architecture and its association with neighboring organelles within the ...[more]