Ontology highlight
ABSTRACT:
SUBMITTER: David Baker
PROVIDER: EMPIAR-12720 | biostudies-other |
REPOSITORIES: biostudies-other

Nature 20240313 8005
A wooden house frame consists of many different lumber pieces, but because of the regularity of these building blocks, the structure can be designed using straightforward geometrical principles. The design of multicomponent protein assemblies, in comparison, has been much more complex, largely owing to the irregular shapes of protein structures<sup>1</sup>. Here we describe extendable linear, curved and angled protein building blocks, as well as inter-block interactions, that conform to specifie ...[more]