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Computationally Designed Nanocage O43_129_+8


ABSTRACT:

SUBMITTER: David Baker 

PROVIDER: EMPIAR-12728 | biostudies-other |

REPOSITORIES: biostudies-other

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Publications


A wooden house frame consists of many different lumber pieces, but because of the regularity of these building blocks, the structure can be designed using straightforward geometrical principles. The design of multicomponent protein assemblies, in comparison, has been much more complex, largely owing to the irregular shapes of protein structures<sup>1</sup>. Here we describe extendable linear, curved and angled protein building blocks, as well as inter-block interactions, that conform to specifie  ...[more]

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