Dataset Information
Micrographs of E. coli CsgA fibril [6000 multi-frame micrographs composed of 40 frames each in TIFF format]
Ontology highlight
ABSTRACT:
SUBMITTER: Bin Liu
PROVIDER: EMPIAR-12788 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Structural insight into <i>Escherichia coli</i> CsgA amyloid fibril assembly.
mBio 20240319 4
The discovery of functional amyloids in bacteria dates back several decades, and our understanding of the <i>Escherichia coli</i> curli biogenesis system has gradually expanded over time. However, due to its high aggregation propensity and intrinsically disordered nature, CsgA, the main structural component of curli fibrils, has eluded comprehensive structural characterization. Recent advancements in cryo-electron microscopy (cryo-EM) offer a promising tool to achieve high-resolution structural ...[more]