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Vibrio cholerae toxin-coregulated pilus machine


ABSTRACT:

SUBMITTER: John William Smith 

PROVIDER: EMPIAR-12852 | biostudies-other |

REPOSITORIES: biostudies-other

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Publications

Architecture of the Vibrio cholerae toxin-coregulated pilus machine revealed by electron cryotomography.

Chang Yi-Wei YW   Kjær Andreas A   Ortega Davi R DR   Kovacikova Gabriela G   Sutherland John A JA   Rettberg Lee A LA   Taylor Ronald K RK   Jensen Grant J GJ  

Nature microbiology 20170206


Type IV pili (T4P) are filamentous appendages found on many Bacteria and Archaea. They are helical fibres of pilin proteins assembled by a multi-component macromolecular machine we call the basal body. Based on pilin features, T4P are classified into type IVa pili (T4aP) and type IVb pili (T4bP)<sup>1,2</sup>. T4aP are more widespread and are involved in cell motility<sup>3</sup>, DNA transfer<sup>4</sup>, host predation<sup>5</sup> and electron transfer<sup>6</sup>. T4bP are less prevalent and  ...[more]

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