Dataset Information
Continuum architecture dynamics of vesicle tethering in exocytosis
Ontology highlight
ABSTRACT:
SUBMITTER: Andres Molina Ribagorda
PROVIDER: EMPIAR-12989 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Continuum architecture dynamics of vesicle tethering in exocytosis.
Cell 20260116 4
Essential for eukaryotes, multiple copies of the exocyst complex tether each secretory vesicle to the plasma membrane (PM) in constitutive exocytosis. The exocyst higher-order structure (ExHOS) that coordinates the action of these multiple exocysts remains unexplored. We integrated particle tracking, super-resolution microscopy, and cryo-electron tomography to time-resolve the continuum conformational landscape of the ExHOS and to functionally annotate its different conformations. We found that ...[more]
