Dataset Information
Surface morphometrics reveals local membrane thickness variation in organellar subcompartments
Ontology highlight
ABSTRACT:
SUBMITTER: Michaela Medina
PROVIDER: EMPIAR-13056 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Surface morphometrics reveals local membrane thickness variation in organellar subcompartments.
bioRxiv : the preprint server for biology 20250501
Lipid bilayers form the basis of organellar architecture, structure, and compartmentalization in the cell. Decades of biophysical, biochemical, and imaging studies on purified or <i>in vitro</i> reconstituted liposomes have shown that variations in lipid composition influence the physical properties of membranes, such as thickness and curvature. However, similar studies characterizing these membrane properties within the native cellular context have remained technically challenging. Recent advan ...[more]