Dataset Information
Glycogen phosphorylase from Dorea longicatena
Ontology highlight
ABSTRACT:
SUBMITTER: Mayu Takai
PROVIDER: EMPIAR-13410 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Structural and mechanistic diversity of glycogen phosphorylases from gut bacteria.
Proceedings of the National Academy of Sciences of the United States of America 20260209 7
Glycogen phosphorylase (GP) plays a central role in glycogen metabolism. While the structure and regulation of mammalian GPs have been extensively studied, the corresponding mechanisms in gut bacterial GPs remain poorly understood. Here, we investigate GPs from <i><i>Escherichia coli</i></i> (<i>Ec</i>GP), <i>Segatella copri</i> (<i>Sc</i>GP), and <i>Dorea longicatena</i> (<i>Dl</i>GP), which represent three phylogenetic clades of GPs, using enzymatic assays, cryo-electron microscopy (cryo-EM), ...[more]