Dataset Information
Complex of RecF-RecO-RecR-DNA from Thermus thermophilus
Ontology highlight
ABSTRACT:
SUBMITTER: Mariusz Czarnocki-Cieciura
PROVIDER: EMPIAR-13465 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination.
Nature structural & molecular biology 20230420 5
In bacteria, one type of homologous-recombination-based DNA-repair pathway involves RecFOR proteins that bind at the junction between single-stranded (ss) and double-stranded (ds) DNA. They facilitate the replacement of SSB protein, which initially covers ssDNA, with RecA, which mediates the search for homologous sequences. However, the molecular mechanism of RecFOR cooperation remains largely unknown. We used Thermus thermophilus proteins to study this system. Here, we present a cryo-electron m ...[more]
